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Specifications

Clone Host Grade Applications Polyclonal Rabbit Serum B IC

Casitas B-lineage lymphoma (Cbl), is an oncogene which causes pre B-cell lymphomas. It participates in the regulation of cell signaling and has the ability to interact with many proteins such as receptor/non-receptor PTK's, structural proteins, and novel proteins that are not well understood. Diseases associated with Cbl are autoimmune diseases, diabetes, and leukemia. By modifying Cbl's ability to bind to oncogenic proteins, Cbl may be developed into an anti-cancer tool and in the near future used in therapeutic intervention.
Catalog #	C0013-26E
Applications
	Suitable for use in Western Blot and Immunocytochemistry. Other applications not tested.
Recommended Dilution	Western Blot: 1:1000
	Immunocytochemistry: 1:500
	Optimal dilutions to be determined by the researcher.
Positive Control	HEK293 cell lysate
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Host	Rabbit
Source	Human
Concentration	Not determined.
Form	Supplied as a liquid in 0.05% sodium azide.
Purity	Serum
Immunogen	Recombinant protein corresponding to the C-terminus of human Cbl (GST-tagged).
Specificity	Recognizes human Cbl. Species Crossreactivity: mouse, rat.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.