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Anti -ErbB3, phosphorylated (Tyr1328) (c-erbB3, HER3)
Anti -ErbB3, phosphorylated (Tyr1328) (c-erbB3, HER3)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH IF |
|
| c-erbB3/HER3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB3 is over expressed in a variety of tumors including breast, stomach pancreas and colon. Heregulin and EGF stimulate tyrosine phosphorylation of c-erbB3 to different extents. | | | Catalog # | C0026-09G | | Applications | Suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence. Other applications not tested. | | Recommended Dilution | Western Blot: 1:500-1:1000 | | Immunohistochemistry: 1:50-1:100 | | Immunofluorescence: 1:100-1:250 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 0.02% sodium azide, 50% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic phosphopeptide corresponding to around the phosphorylation site of tyrosine 1328 (P-D-YP-W-H) from human HER3/ErbB3. | | Specificity | Recognizes endogenous levels of human HER3/ErbB3 only when phosphorylated at tyrosine 1328. Species Crossreactivity: Mouse, rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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