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You are here:Home » Antibodies » Abs to Carbohydrates, Glycoproteins » Anti -C4.4A (LYPD3, Y6/PLAUR domain containing 3 GPI-anchored metastasis-associated protein C4.4A homolog, Ly6/PLAUR domain-containing protein 3 precursor, Matrigel-induced gene C4 protein, MIG-C4, UNQ491/PRO1007)

Anti -C4.4A (LYPD3, Y6/PLAUR domain containing 3 GPI-anchored metastasis-associated
protein C4.4A homolog, Ly6/PLAUR domain-containing protein 3 precursor, Matrigel-induced
gene C4 protein, MIG-C4, UNQ491/PRO1007)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
LYPD3 (Ly6/PLAUR-domain containing protein 3; also MIG-C4 and GPI-anchored metastasis-associated protein C4.4A) is an 85-95kD, variably glycosylated member of the Ly6 family of GPI-anchored proteins. It is expressed on transitional epithelium, keratinocytes and monocytes, and binds laminin 1 and 5, plus Galectin-3. LYPD3 is believed to support cell migration. Mature human LYPD3 is a 296aa GPI-linked glycoprotein. It contains two UPAR domains (aa33-126 and 140-222), and an ADAM cleavage site (aa312-325). The molecule shows extensive N- and O-linked glycosylation. There is one potential isoform that shows a deletion of aa129-180. Over aa31-286, human LYPD3 shares 81%aa identity with mouse LYPD3.
Catalog #C0045-75C
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 15ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to human LYPD3 at C-terminal (KLH).
SpecificityRecognizes human LYPD3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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