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You are here:Home » Antibodies » Abs to Cancer Markers » Anti -CA125 Cancer Antigen (Mucin 16, MUC16, MUC-16, CA125, CA-125, Cancer Antigen 125, FLJ14303, Mucin 16 Cell Surface Associated, Cancer-related Tumor Marker CA125, Ovarian Carcinoma Antigen CA125)

Anti -CA125 Cancer Antigen (Mucin 16, MUC16, MUC-16, CA125, CA-125, Cancer Antigen 125,
FLJ14303, Mucin 16 Cell Surface Associated, Cancer-related Tumor Marker CA125, Ovarian
Carcinoma Antigen CA125)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B
CA125/MUC16 is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is over expressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000kD with smaller 'subunits' being described by some investigators.
Catalog #C0050-01D
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionsWestern Blot: 1-5ug/ml after electrophoresing 20ug of sample.
Optimal dilutions to be determined by the researcher.
Recommended PairDetection: C0050-01D
Capture: M4701-95B
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
CAS NumberN/A
Clone TypeMonoclonal
IsotypeIgG1
Clone No8J453
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 10mM Tris, pH 7.5, 0.15M sodium chloride, 0.05% sodium azide.
PurityPurified by Ion Exchange chromatography.
ImmunogenCA-125 purified from human ovarian carcinoma.
Cellular LocalizationCell Membrane
SpecificityRecognizes human ovarian carcinoma cells. Specifically recognizes epitope specificity group B (ISOBM classification).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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