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You are here:Home » Antibodies » Abs to Cancer Markers » Anti -CA125 Cancer Antigen (Ovarian Cancer)

Anti -CA125 Cancer Antigen (Ovarian Cancer)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
CA125 antigen is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is overexpressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that CA125 is a high molecular mass glycoprotein. CA125 contains three antigenic domains: A-domain (Oc125), B-domain (M11), C-Domain (Ov197). The CA-125 antigen is present on a mucin-like glycoprotein of >200kD and is detectable on the apical surface of normal endometrium and endocervix.
Catalog #C0050-01H
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Matched PairC0050-01J and C0050-01H
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9F413
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenAffinity purified human CA 125 antigen.
SpecificityRecognizes human CA 125, “M-11 like” Group B
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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