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Anti -CA125 Cancer Antigen, B Domain (Ovarian Cancer)
Anti -CA125 Cancer Antigen, B Domain (Ovarian Cancer)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Highly Purified |
E B IH |
|
| Catalog # | C0050-16 | | According to the ISOBM-TD-1 workshop, CA125 contains three antigenic domains | A-domain (Oc125), B-domain (M11), C-Domain (Ov197). The CA-125 antigen is present on a mucin-like glycoprotein of > 200kD and is detectable on the apical surface of normal endometrium and endocervix. | | Applications | Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications have not been tested. | | Recommended Dilution | Immunohistochemistry: Paraffin-embedded tissues | | Optimal dilutions to be determined by the researcher. | | Hybridoma | Hybridization of Sp2/0 myeloma cells with spleen cells from Balb/c mice. | | Source | Ascites | | Recommended Pair | Detection: C0050-16 | | Capture: C0050-13 | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | N/A | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 1.B.830 | | Host | Mouse | | Source | Human | | Concentration | ~7mg/ml | | Form | Supplied as a liquid in 10mM Tris, 0.15M sodium chloride, pH 7.5, 0.1% sodium azide. | | Purity | Purified by Ion Exchange Chromatography. | | Immunogen | CA125 antigen purified from human ovarian carcinoma (MW > 1000kD) | | Specificity | Recognizes B-domain in the protein core of the human CA125 ovarian cancer antigen. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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