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You are here:Home » Antibodies » Antibodies-Cancer Markers » Anti -CA125 Cancer Antigen (Ovarian Cancer)

Anti -CA125 Cancer Antigen (Ovarian Cancer)


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Clone Host Grade Applications
Monoclonal Mouse Supernatant E IH
CA125 determinant is present on a high molecular weight, mucin like glycoprotein of high molecular weight. CA125 has been found on frozen sections of amnion and derivatives of coelomic and mullerian epithelium, including pleura, pericardium and peritoneum.4 In adult tissues, epithelial cells of fallopian tube, endometrium and endocervix (4); pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland and mammary gland (5,6). It is also found in mesothelial cell lining of pleura, pericardium and peritoneum. It is found in ovarian tumors of serous, endometrioid or clear cell types and adenocarcinomas of mullerian type.
Catalog #C0050-17F
ApplicationsImmunohistology (Formalin/paraffin): (Use Ab at 1:20-1:40 for 30 min at RT) Staining of formalin-fixed tissues REQUIRES boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.
Positive Control Colon carcinoma.
Cellular Localization Extracellular membrane-associated
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No5G20
ConcentrationNot determined
FormSupplied as a liquid with 0.09% sodium azide.
PurityCulture supernatant
ImmunogenCA125 antigen derived from ascites fluid.
SpecificityRecognizes CA125. Species Crossreactivity: Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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