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You are here:Home » Antibodies » Abs to Cancer Markers » Anti -CA19-9 Cancer Antigen (Pancreatic, GI or Ovarian Tumor Antigen, Sialyl Lewis a)

Anti -CA19-9 Cancer Antigen (Pancreatic, GI or Ovarian Tumor Antigen, Sialyl Lewis a)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified IH
CA19-9 is a carbohydrate antigenic determinant identified as a sialylated lacto-N-fucopentose II, an oligosaccharide biochemically related to the Lewis A blood group antigen. In malignant tissues positive staining of tumor cells is observed in most adenocarcinomas of the pancreas and stomach and in a large proportion of colon and gall bladder tumors. The antigen is also expressed in approximately half of primary and metastatic ovarian tumors. In normal tissues positive staining is also observed in columnor epithelium of the pancreas stomach, liver, gall bladder and in bronchial glands of the lung.
Catalog #C0075-13B
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry (Frozen and parrafin): 1:10-1:40
Note: A minimum incubation time of 1 hour is recommended. Does not require protein digestion pre-treatment of paraffin sections. Does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
Optimal working dilutions to be determined by researcher.
Recommended Secondary ReagentsI1904-65W: IgG, F(abí)2 (HRP) Pab RbxMo
I1904-66C: IgG, F(abí)2, X-Adsorbed (HRP) Pab RbxMo
Recommended Positive Control TissueAdenocarcinoma of colon
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No3H606
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, 1% BSA, 0.1% sodium azide.
PurityPurified
ImmunogenSW1116 human colorectal cancer cells.
SpecificityRecognizes human CA19-9 Cancer Antigen.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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