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You are here:Home » Antibodies » Abs to Cancer Markers » Anti -CA19-9 Cancer Antigen (Pancreatic, GI or Ovarian Tumor Antigen, Sialyl Lewis a)

Anti -CA19-9 Cancer Antigen (Pancreatic, GI or Ovarian Tumor Antigen, Sialyl Lewis a)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified IH
CA199, a carbohydrate antigenic determinant identified as a sialylated lacto-N-fucopentose II, is an oligosaccharide which is biochemically related to the sialyl Lewis a (sialyl Lea) blood group substance. CA199 is detected is most adenocarcinomas of the pancreas and stomach, and many colon and gall bladder cancers. The antigen is also expressed in approximately half of primary and metastatic ovarian tumors. The immunostaining pattern of CA199 antigen may be of value in predicting the prognosis of patients with colorectal carcinoma. In normal tissues, positive staining is observed in columnar epithelium of the pancreas, stomach, liver, gall bladder and in bronchial glands of the lung.
Catalog #C0075-29
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry: Frozen and formalin-fixed, paraffin embedded tissue sections. Epitope retrieval and enzyme digestion are not required.
Optimal dilutions to be determined by the researcher.
Positive ControlHuman colorectal adenocarcinoma tissue
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No3G37
HostMouse
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid in PBS, pH 7.2, 1% BSA, 0.1% sodium azide.
PurityPurified
ImmunogenPuri ed human CA199 protein.
Expected Staining PatternMembrane
SpecificityRecognizes human CA19-9 Cancer Antigen.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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