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You are here:Home » Antibodies » Abs to Ion Channel » Anti -CACNA2D2 (KIAA0558, Voltage-dependent Calcium Channel Subunit alpha-2/delta-2, Voltage-gated Calcium Channel Subunit alpha-2/delta-2)

Anti -CACNA2D2 (KIAA0558, Voltage-dependent Calcium Channel Subunit alpha-2/delta-2,
Voltage-gated Calcium Channel Subunit alpha-2/delta-2)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
Cacna2d2 is an alpha subunit 2/delta regulatory subunit of the voltage-gated calcium channel. The human Cacna2d2 corresponds to the mouse mutant ducky phenotype, which is a model for absence epilepsy, characterized by seizures and ataxia. CACNA2D2 overexpression has been implicated in the apoptosis of NSCLC cells by changing the intracellular calcium concentration and disrupting the mitochondrial membrane.
Catalog #C0104-70Q
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:1000
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No3A4
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant corresponding to aa65-163 from human CACNA2D2 with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human CACNA2D2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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