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You are here:Home » Antibodies » Abs to Ion Channel » Anti -CACNB2 (Calcium channel, voltage-dependent, beta 2 subunit, CAB2, CACNLB2, EA5, EJM, dihydropyridine-sensitive L-type)

Anti -CACNB2 (Calcium channel, voltage-dependent, beta 2 subunit, CAB2, CACNLB2, EA5, EJM,
dihydropyridine-sensitive L-type)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. The beta subunit of voltage-dependent calcium channels aids the function of the calcium channel by increasing the peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. CAB2 is a membrane protein that is expressed in all tissues. The unprocessed precursor is 660 amino acids in length and has a predicted molecular weight of 74.5KDa. It belongs to the calcium channel beta subunit family and contains one SH3 domain. CAB2 is involved in the MAPK signalling pathway and is also associated with Lambert-Eaton myasthenic syndrome.
Catalog #C0104-81
ApplicationsSuitable for use in Western Blot and ELISA. Other applications not tested.
Recommended DilutionELISA: 0.1ng/ml
Optimal dilution determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No9G323
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from PBS, pH 7.2. Reconstitute in 100ul of sterile H2O.
PurityPurified by affinity chromatography.
ImmunogenPartial recombinant protein of human CAB2 (aa 213-301) with a GST tag.
SpecificityRecognizes human CACNB2. Species crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesVoltage-dependent L-type calcium channel subunit beta-2, calcium channel voltage-dependent subunit beta 2, Lambert-Eaton myasthenic syndrome antigen B, MYSB, GENE NAME: CACNB2


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