Anti -Cadherin N (CDH2, Cadherin 2, type 1, N-cadherin (neuronal), Cadherin-2, Cadherin-2
precursor, CD325, CD325 antigen, CDHN, CDw325, CDw325 antigen, NCAD, N-cadherin,
Neural-cadherin, Neural-cadherin precursor)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
IH |
|
| Cadherins are transmembrane glycoproteins involved in Ca++ dependent cell adhesion (1). The cadherin family, including (E)pithelial-Cadherin, (N)euronal-Cadherin, (P)lacental-Cadherin and (R)etinal-Cadherin, plays an important role in tissue morphogenesis and structure. N-cadherin (136kD) is expressed in nerve cells, developing skeletal muscle, embryonic and mature cardiac muscle cells, and pleural mesothelial cells. | | | Studies have indicated that analysis of E-cadherin and N-cadherin expression may be useful in differentiating pleural mesotheliomas (N-cadherin positive) and lung adenocarcinomas (E-cadherin positive) (2). | | | Catalog # | C0107-03 | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. Other applications not tested. | | Recommended Dilution | Immunohistochemistry: Formalin-fixed, paraffin-embedded sections. 1:50-1:100 Citrate buffer, pH6.0 retrieval required | | Optimal dilutions to be determined by the researcher. | | Recommended Positive Control | Brain, pancreas | | Expected Staining Pattern | Membrane | | Epitope Retrieval | Required (Citrate buffer, pH6.0). | | Enzyme Digestion | Not required | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Clone No | 3G40 | | Host | Mouse | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.1% sodium azide. | | Purity | Purified. | | Immunogen | Recombinant protein corresponding to an intracellular domain of chicken N-cadherin. | | Specificity | Recognizes human N-cadherin. Does not crossreact with other cadherin family members including P- and E-cadherins. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Cadherin N (CDH2, Cadherin 2, type 1, N-cadherin (neuronal), Cadherin-2, Cadherin-2 precursor, CD325, CD325 antigen, CDHN, CDw325, CDw325 antigen, NCAD, N-cadherin, Neural-cadherin, Neural-cadherin precursor) |
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