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You are here:Home » Antibodies » Abs to Cadherin » Anti -Cadherin N (Cadherin-2, CDw325, Neural Cadherin, N-cadherin, CD325, CDH2, CDHN, NCAD)

Anti -Cadherin N (Cadherin-2, CDw325, Neural Cadherin, N-cadherin, CD325, CDH2, CDHN,
NCAD)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH IF
N-cadherin (NCAD) is a member of the cadherin cell-cell adhesion receptor family that includes P-, E-,and R-cadherin and liver cell adhesion molecule (L-CAM). N-Cadherin, also known as Cadherin-2, encodes a 907aa protein that includes a 159aa signal sequence. Human and mouse nucleotide sequences are 96% identical. Mouse Ncad gene consists of 16 exons dispersed over more than 200kb of genomic DNA. Human N-cadherin gene contains 16 exons and its sequence is highly similar to both the mouse NCAD gene (including the large first and second introns) and other cadherin genes. N-cadherin is mapped to 18q11.2. Cadherin regulates dendritic spine morphogenesis.
Catalog #C0107-03D
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, and Immunofluorescence. Other applications not tested.
Recommended DilutionWestern Blot: 2ug/ml
Immunohistochemistry (frozen): 4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10K117
HostMouse
SourceChicken
ConcentrationAs reported
FormSupplied as a liquid.
PurityPurified by immunoaffinity chromatography.
ImmunogenAffinity purified chicken heart A-CAM.
SpecificityRecognizes chicken N-Cadherin. Species crossreactivity: mouse, rat, rabbit, human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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