Anti -Cadherin N (Cadherin-2, CDw325, Neural Cadherin, N-cadherin, CD325, CDH2, CDHN, NCAD)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IH IF |
|
| N-cadherin (NCAD) is a member of the cadherin cell-cell adhesion receptor family that includes P-, E-,and R-cadherin and liver cell adhesion molecule (L-CAM). N-Cadherin, also known as Cadherin-2, encodes a 907aa protein that includes a 159aa signal sequence. Human and mouse nucleotide sequences are 96% identical. Mouse Ncad gene consists of 16 exons dispersed over more than 200kb of genomic DNA. Human N-cadherin gene contains 16 exons and its sequence is highly similar to both the mouse NCAD gene (including the large first and second introns) and other cadherin genes. N-cadherin is mapped to 18q11.2. Cadherin regulates dendritic spine morphogenesis. | | | Catalog # | C0107-03D | | Applications | Suitable for use in Western Blot, Immunohistochemistry, and Immunofluorescence. Other applications not tested. | | Recommended Dilution | Western Blot: 2ug/ml | | Immunohistochemistry (frozen): 4ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 10K117 | | Host | Mouse | | Source | Chicken | | Concentration | As reported | | Form | Supplied as a liquid. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Affinity purified chicken heart A-CAM. | | Specificity | Recognizes chicken N-Cadherin. Species crossreactivity: mouse, rat, rabbit, human. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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