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You are here:Home » Antibodies » Abs to Cadherin » Anti -Cadherin N (Cadherin-2, CDw325, Neural Cadherin, N-cadherin, CD325, CDH2, CDHN, NCAD)

Anti -Cadherin N (Cadherin-2, CDw325, Neural Cadherin, N-cadherin, CD325, CDH2, CDHN,
NCAD)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites IH
Cadherins are a family of transmembrane glycoproteins responsible for maintaining the integrity of tissue and are involved in cell differentiation, cell migration and intracellular adhesion through a calcium dependent mechanism characterized by homotypic adhesion.Their highly conserved cytoplasmic domains associated with catenins, thus mediating contact between cadherins and the microfilaments of cytoskeleton. Each cadherin subclass, shows a unique tissue distribution with E-cadherin expressed in epithelial cells and P-cadherin restricted to decidua tissue and the basal or lower layers of stratified epithelium. Cadherins are expressed in a tissue specific manner and and are required for assembly of cells into solid tissue. Cadherins play an important part in tumor invasion and metastasis.
Catalog #C0107-03H
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (formalin fixed paraffin embedded): 1:25-1:50 (ABC)
Optimal dilutions to be determined by the researcher.
Positive ControlTonsil
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11E38
HostMouse
SourceChicken
ConcentrationNot determined.
FormSupplied as a liquid, sodium azide.
PurityAscites
ImmunogenSynthetic peptide corresponding to the C-terminal of chicken N-Cadherin with extra N-terminal lysine residue. Cellular Localization: Cell membrane
SpecificityRecognizes chicken Cadherin, pan. Species Crossreactivity: bovine, feline, canine, goat, guinea pig, hamster.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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