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You are here:Home » Antibodies » Abs to Cadherin » Anti -Cadherin 6 (K-Cadherin, Fetal Kidney, CDH6)

Anti -Cadherin 6 (K-Cadherin, Fetal Kidney, CDH6)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant IH
The cadherin gene family encodes calcium-dependent adhesion molecules that promote homophilic interactions among cells. All cadherins are single-pass transmembrane proteins with a variable number of extracellular domains (EC; 110 amino acids long). Classical cadherins consist of five EC domains and a conserved cytoplasmic domain and are divided in type I and type II subgroups. Type I comprises cadherin E, N, P, and R. Type II include cadherin-5, -6, -8, -11, and -12. During embryogenesis differential expression of cadherins can drive morphogenesis by stimulating cell aggregation, defining boundaries between groups of cells and promoting cell migration. Cadherin-6 seems to be required for the early aggregation of induced mesenchymal cells and their subsequent conversion to epithlium.
Catalog #C0107-05A
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry (Frozen): Paraformaldehyde fixed, with 0.2% Triton X-100 in PBS. Incubate for 1 hr at RT or overnight at 4°C.
Optimal dilutions to be determined by the researcher.
Positive ControlEmbryonic kidney (e.g. establishment of developmental pattern of nephrons).
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypeMonoclonal
IsotypeIgG1
Clone No5F95
HostMouse
ConcentrationNot Determined
FormSupplied as a liquid, 0.09% sodium azide.
PuritySupernatant
ImmunogenGST fusion protein corresponding to part of the extracellular domain of Cadherin 6
SpecificityRecognizes Cadherin 6. Species Crossreactivity: human
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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