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Anti -Cadherin 6 (K-Cadherin, Fetal Kidney, CDH6)
Anti -Cadherin 6 (K-Cadherin, Fetal Kidney, CDH6)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
IH |
|
| The cadherin gene family encodes calcium-dependent adhesion molecules that promote homophilic interactions among cells. All cadherins are single-pass transmembrane proteins with a variable number of extracellular domains (EC; 110 amino acids long). Classical cadherins consist of five EC domains and a conserved cytoplasmic domain and are divided in type I and type II subgroups. Type I comprises cadherin E, N, P, and R. Type II include cadherin-5, -6, -8, -11, and -12. During embryogenesis differential expression of cadherins can drive morphogenesis by stimulating cell aggregation, defining boundaries between groups of cells and promoting cell migration. Cadherin-6 seems to be required for the early aggregation of induced mesenchymal cells and their subsequent conversion to epithlium. | | | Catalog # | C0107-05A | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry (Frozen): Paraformaldehyde fixed, with 0.2% Triton X-100 in PBS. Incubate for 1 hr at RT or overnight at 4°C. | | Optimal dilutions to be determined by the researcher. | | Positive Control | Embryonic kidney (e.g. establishment of developmental pattern of nephrons). | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 5F95 | | Host | Mouse | | Concentration | Not Determined | | Form | Supplied as a liquid, 0.09% sodium azide. | | Purity | Supernatant | | Immunogen | GST fusion protein corresponding to part of the extracellular domain of Cadherin 6 | | Specificity | Recognizes Cadherin 6. Species Crossreactivity: human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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