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You are here:Home » Antibodies » Abs to Cadherin » Anti -CDH23 (Cadherin-23, Cadherin 23, Otocadherin, KIAA1774, KIAA1812, UNQ1894/PRO4340)

Anti -CDH23 (Cadherin-23, Cadherin 23, Otocadherin, KIAA1774, KIAA1812, UNQ1894/PRO4340)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
Catalog #C0107-23A
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1000
Western Blot: 1-3ug/ml, observed in human brain (amygdala and frontal cortex lysates) on ~60kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-YNISLYENVTVGTS, from human CDH23, at the internal region of the protein (NP_071407.3, NP_443068.1).
SpecificityRecognizes human CDH23.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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