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You are here:Home » Antibodies » Antibodies-Cadherin » Anti -CDH1, NT (E-Cadherin, Epithelial Cadherin, Uvomorulin, Cadherin-1, CAM 120/80, CD324, UVO) (PE)

Anti -CDH1, NT (E-Cadherin, Epithelial Cadherin, Uvomorulin, Cadherin-1, CAM 120/80,
CD324, UVO) (PE)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B FC
CDH1 is a classical cadherin from the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization.
Catalog #C0108-25P-PE
ApplicationsSuitable for use in Western Blot and Flow Cytometry. Other applications not tested.
Recommended DilutionsFlow Cytometry: 1:10-1:50
Western Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityStore product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note Applications are based on unconjugated antibody.
Clone TypePolyclonal
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to a region betwen a portion within aa160-189 from the N-terminal region of human CDH1, conjugated to KLH.
SpecificityRecognizes human CDH1 at ~97kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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