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You are here:Home » Antibodies » Abs to Cadherin » Anti -Cadherin M

Anti -Cadherin M

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B IC
Cadherin M is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. This protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation.
Catalog #C0108-34Z
ApplicationsSuitable for use in ELISA, Western Blot, Immunocytochemistry.
Other applications not tested.
Recommended DilutionsELISA: 0.05ug/ml
Western Blot: 1ug/ml for AP/BCIP/NBT (MTT) detection and 0.5ug/ml for HRPO/ECL detection.
Immunocytochemistry (Immunofluorescence): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No6D190
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, 0.1% sodium azide, PEG and Sucrose.
PurityPurified by subsequent thilliophillic adsorption and size exclusion chromatography.
ImmunogenRecombinant extracellular domain of human M-cadherin
SpecificityRecognizes human M-Cadherin. Does not cross-react with mouse M-cadherin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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