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You are here:Home » Antibodies » Antibodies-Cadherin » Anti -Cadherin M

Anti -Cadherin M

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B IC
Cadherin M is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. This protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation.
Catalog #C0108-34Z
ApplicationsSuitable for use in ELISA, Western Blot and Immunofluorescence/Immunocytochemistry.
Other applications not tested.
Recommended DilutionsELISA: 0.05ug/ml
Western Blot: 0.5ug/ml for HRPO/ECL detection. Use Casein/Tween 20 blocking buffer.
Immunofluorescence (Immunocytochemistry): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No6D190
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a lyophilized powder from PBS, 0.09% sodium azide, PEG and sucrose.
PurityPurified by subsequent thilliophillic adsorption and size exclusion chromatography.
ImmunogenRecombinant extracellular domain of human M-cadherin.
EpitopeExtracellular domain
SpecificityRecognizes human M-Cadherin at 130kD. Does not cross-react with mouse M-cadherin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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