Anti -Cadherin N (CDH2, Cadherin 2, type 1, N-cadherin (neuronal), Cadherin-2, Cadherin-2
precursor, CD325, CD325 antigen, CDHN, CDw325, CDw325 antigen, NCAD, N-cadherin,
Neural-cadherin, Neural-cadherin precursor)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
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| Cadherins are transmembrane glycoproteins involved in Ca++ dependent cell adhesion (1). The cadherin family, including (E)pithelial-Cadherin, (N)euronal-Cadherin, (P)lacental-Cadherin and (R)etinal-Cadherin, plays an important role in tissue morphogenesis and structure. N-cadherin (136kD) is expressed in nerve cells, developing skeletal muscle, embryonic and mature cardiac muscle cells, and pleural mesothelial cells. Studies have indicated that analysis of E-cadherin and N-cadherin expression may be useful in differentiating pleural mesotheliomas (N-cadherin positive) and lung adenocarcinomas (E-cadherin positive). | | | Catalog # | C0108-35C | | Applications | | | Suitable for use in Immunohistochemistry and Western Blot. | | Other applications not tested. | | Recommended Dilutions | Immunohistochemistry (Frozen and paraffin): 5-10ug/ml | | Western Blot: 5-10ug/ml | | Optimal dilution to be determined by researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~2mg/ml (after reconstitution) | | Form | Supplied as a lyophilized powder from PBS, pH 7.4, 1% BSA. Reconstitute with 200ul sterile ddH2O. Dilute with 20mM TBS, pH 7.4, 1% BSA, 0.1% sodium azide, 10mM calcium chloride. (PBS may cause precipitation) | | Purity | Purified by Protein A affinity chromatography | | Immunogen | Synthetic peptide corresponding to aa 808-827 of human N-cadherin. | | Specificity | Recognizes human N-cadherin. Species Crossreactivity: mouse, bovine and chicken. Does not cross-eact with human E- or P-cadherin. Does not inhibit N-cadherin dependent cell-cell contact. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Cadherin N (CDH2, Cadherin 2, type 1, N-cadherin (neuronal), Cadherin-2, Cadherin-2 precursor, CD325, CD325 antigen, CDHN, CDw325, CDw325 antigen, NCAD, N-cadherin, Neural-cadherin, Neural-cadherin precursor) |
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