Anti -Cadherin N (CDH2, Cadherin 2, type 1, N-cadherin (neuronal), Cadherin-2, Cadherin-2
precursor, CD325, CD325 antigen, CDHN, CDw325, CDw325 antigen, NCAD, N-cadherin,
Neural-cadherin, Neural-cadherin precursor)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
B IH IC |
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| Cadherins are transmembrane glycoproteins involved in Ca++ dependent cell adhesion (1). The cadherin family, including (E)pithelial-Cadherin, (N)euronal-Cadherin, (P)lacental-Cadherin and (R)etinal-Cadherin, plays an important role in tissue morphogenesis and structure. N-cadherin (136kD) is expressed in nerve cells, developing skeletal muscle, embryonic and mature cardiac muscle cells, and pleural mesothelial cells. | | | Studies have indicated that analysis of E-cadherin and N-cadherin expression may be useful in differentiating pleural mesotheliomas (N-cadherin positive) and lung adenocarcinomas (E-cadherin positive). | | | Catalog # | C0108-35K | | Applications | Suitable for use in Western Blot, Immunocytochemistry and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 5-10ug/ml. Use under non-reducing and non-heating conditions. Band at ~99.9kD | | Immunohistochemistry (Frozen/paraffin: 5-10ug/ml. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add glycerol (40-50%) and aliquot. Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not Determined | | Form | Supplied as a liquid in PBS. pH 7.4. | | Purity | Serum | | Immunogen | Synthetic peptide representing amino acids 808-827 (RMDERPIHAEPQYPVRSAAP) of human N-Cadherin. | | Localization | Type I membrane protein. | | Specificity | Recognizes human Cadherin N. Does not react with human E or P Cadherin. It does not inhibit N Cadherin dependent cell-cell contact. Species Crossreactivity: mouse, bovine and chicken. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | NCAD |
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Download Specifications for Anti -Cadherin N (CDH2, Cadherin 2, type 1, N-cadherin (neuronal), Cadherin-2, Cadherin-2 precursor, CD325, CD325 antigen, CDHN, CDw325, CDw325 antigen, NCAD, N-cadherin, Neural-cadherin, Neural-cadherin precursor) |
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