Anti -Cadherin N (CDH2, Cadherin 2, type 1, N-cadherin (neuronal), Cadherin-2, Cadherin-2
precursor, CD325, CD325 antigen, CDHN, CDw325, CDw325 antigen, NCAD, N-cadherin,
Neural-cadherin, Neural-cadherin precursor)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Supernatant |
B |
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| The cadherins are a large family of cell adhesion molecules involved in calcium-dependent recognition and adhesion events. The cadherin subfamily includes N-, P-, R-, B-, and E- cadherins, and other members (1). Synaptic remodeling has been postulated as a mechanism underlying synaptic plasticity, and cadherin adhesion molecules are thought to be a regulator of such a process. Findings suggest that cadherin regulates dendritic spine morphogenesis and related synaptic functions, presumably cooperating with cadherin-independent adhesive mechanisms to maintain spine-axon contacts (2). Retinoblastoma cells, in contrast with normal retina, express an N-cadherin (cadherin-2)/catenin complex that is irregularly distributed and weakly linked to the cytoskeleton. In retinoblastoma, this complex acts as an invasion promoter (3). | | | Catalog # | C0108-35S | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:5000-1:20,0000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 9E167 | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 50 mM Tris-Glycine, pH 7.4, 0.15 M sodium chloride, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. | | Purity | Supernatant | | Immunogen | A synthetic peptide corresponding to residues in the extracellular region of human N-Cadherin | | Specificity | Recognizes human N-Cadherin. Species crossreactivity: mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Neural cadherin, N-cadherin, CDw325, CD325 antigen |
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Download Specifications for Anti -Cadherin N (CDH2, Cadherin 2, type 1, N-cadherin (neuronal), Cadherin-2, Cadherin-2 precursor, CD325, CD325 antigen, CDHN, CDw325, CDw325 antigen, NCAD, N-cadherin, Neural-cadherin, Neural-cadherin precursor) |
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