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You are here:Home » Antibodies » Abs to Cadherin » Anti -Cdh-1, ID (E-cadherin, cdh1)

Anti -Cdh-1, ID (E-cadherin, cdh1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Cadherins are calcium dependent cell adhesion molecules. E- cadherin, also known as cdh1, is expressed during early embryogenesis in blastomeres, the anterior mesoderm during gastrulation, and developing epithelial structures. Cdh1 was detected at the pharyngula stage in the midbrain-hindbrain boundary. Morpholino knockdown of E-cadherin in embryo studies was found to reduce embryo survivability; early embryonic cdh1 MO knockdown resulted in irregular cleavage plane orientation between blastomeres. Cdh1 knockdown also resulted in inhibited epiboly cell movements and gastrulation cell movements. Prechordal plate derivatives were also absent in Cdh1 knockdowns. Co-injection with E-cadherin mRNA served to demonstrate the specific activity of E-cadherin morpholino knockdown.
Catalog #C0108-40
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:5000-1:20,000
Western Blot: 1:500-1:1000
Optimal dilutions to be determined by the researcher.
Control Peptide C0108-40D
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceZebrafish
ConcentrationNot determined
FormSupplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.05% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the intermediate region of zebrafish Cdh-1.
SpecificityRecognizes zebrafish Cdh-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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