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You are here:Home » Antibodies » Abs to Cadherin » Anti -Cadherin T, NT (Truncated Cadherin, Cadherin 13, Heart-Cadherin)

Anti -Cadherin T, NT (Truncated Cadherin, Cadherin 13, Heart-Cadherin)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IF
T-cadherin was initially identified as cadherin-type cell adhesion molecule expressed in various neuronal populations in a temporally and spatially restricted pattern during axon growth. T-cadherin is an atypical member of the cadherin family because it does not possess the typical transmembrane and cytoplasmic domains but is instead anchored to the plasma membrane by glycosylphosphatidylinositol (GPI) linkage. T-cadherin may play a role in malignant tumor development as loss of the chromosome locus containing the T-cadherin gene
correlates with the development of a variety of cancers. Recently it has been shown that T-cadherin can act as a receptor for hexameric and high-molecular weight forms of adiponectin, suggesting that T-cadherin may also play a role in metabolic regulation.
Catalog #C0108-50B
ApplicationsSuitable for use in Western Blot and Immunofluorescence. Other applications not tested.
Recommended DilutionsWestern Blot: 0.5-1ug/ml
Immunofluorescence: 20ug/ml
Optimal dilution determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to 15aa near the amino terminus of human T-cadherin (Genbank accession No. NM_001248).
SpecificityRecognizes human T-cadherin. Species Crossreactivity: mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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