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You are here:Home » Antibodies » Antibodies-Enzymes, Phosphatase » Anti -Calcineurin A (CnA, Protein Phosphatase 2B, A subunit)

Anti -Calcineurin A (CnA, Protein Phosphatase 2B, A subunit)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Calcineurin is a heterodimer protein that binds to Ca2+. A Ca2+/calmodulin-regulated protein phosphatase, it is composed of a 19 kD calcineurin B (CnB) and a 61 kD calmodulin-binding catalytic subunit, calcineurin A (CnA). Calcineurin A was first detected in skeletal muscle and brain tissues, but it has since been found in all cell types, from yeast to mammalian. Calcineurin A may be responsible for the calmodulin activation property of calcineurin. There is evidence suggesting that alternative splicing could give rise to different forms of calcineurin A.
Catalog #C0114-06A
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 0.05-0.2ug/ml
Western Blot: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
Clone TypePolyclonal
Concentration~0.5mg/ml (after reconstitution)
FormSupplied as a lyophilized powder in PBS, pH 7.4, 0.02% sodium azide. Reconstitute with 80ul sterile ddH2O.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide (KLH). within the amino terminal of human calcineurin A protein (Swiss Prot: Q08209).
SpecificityRecognizes endogenous levels of human calcineurin A protein. Species Crossreactivity: mouse. Expected to cross-react with rat based on sequence homology.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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