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You are here:Home » Antibodies » Abs to Enzymes, Phosphatase » Anti -Calcineurin A (CnA, Protein Phosphatase 2B, A subunit)

Anti -Calcineurin A (CnA, Protein Phosphatase 2B, A subunit)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Calcineurin is a heterodimer protein that binds to Ca2+. A Ca2+/calmodulin-regulated protein phosphatase, it is composed of a 19 kD calcineurin B (CnB) and a 61 kD calmodulin-binding catalytic subunit, calcineurin A (CnA). Calcineurin A was first detected in skeletal muscle and brain tissues, but it has since been found in all cell types, from yeast to mammalian. Calcineurin A may be responsible for the calmodulin activation property of calcineurin. There is evidence suggesting that alternative splicing could give rise to different forms of calcineurin A.
Catalog #C0114-06B
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 0.05-0.2ug/ml
Western Blot: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide within residues 450-500 of human calcineurin A protein (Swiss Prot: Q08209).
SpecificityRecognizes endogenous levels of calcineurin A protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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