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Anti -Calcipressin 1, CT (DSCR1, Regulator Of Calcineurin 1, DSCR1, Down Syndrome Critical Region Protein 1, Myocyte-enriched Calcineurin-interacting Protein 1, MCIP1, Adapt78, RCAN1, DSC1, CSP1)
Anti -Calcipressin 1, CT (DSCR1, Regulator Of Calcineurin 1, DSCR1, Down Syndrome Critical Region Protein 1, Myocyte-enriched Calcineurin-interacting Protein 1, MCIP1, Adapt78, RCAN1, DSC1, CSP1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B |
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| DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. The gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of DSCR1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease. | | | Catalog # | C0114-85A | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:1,000 | | Western Blot: 1:100-1:500 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.25mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide selected from the C-terminal region of human DSCR1 (KLH). | | Specificity | Recognizes human DSCR1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Calcipressin 1, CT (DSCR1, Regulator Of Calcineurin 1, DSCR1, Down Syndrome Critical Region Protein 1, Myocyte-enriched Calcineurin-interacting Protein 1, MCIP1, Adapt78, RCAN1, DSC1, CSP1) |
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