Anti -Calcitonin Gene Related Peptide (CGRP, Calcitonin Gene-related Peptide 1, CGRP1,
Calcitonin Gene-related Peptide I, CGRP I, CGRP-I, Alpha Type CGRP, CAL6, Cal1, Calc,
Calcitonin 1, CALC 1, CALC 2, RATCAL6, Calcitonin-related Polypeptide alpha, CALC A, CAL
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E IH IF |
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| CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin. Despite these important physiologic functions, therapeutic strategies using CGRP have been impeded due to the lack of a cloned CGRP receptor with which ligands could be developed. | | | Catalog # | C0115-01D | | Applications | Suitable for use in ELISA, Immunofluorescence and Immunohistochemistry (Paraffin). Not recommended for frozen or resin sections. Other applications not tested. | | Recommended Dilutions | ELISA: 1:500-1:2500 | | Optimal dilutions to be determined by the researcher. | | Recommended Secondary Antibodies | I1904-28K: IgG, H&L (HRP) Pab RbxGt | | I1904-28Q: IgG, H&L, X-Adsorbed (HRP) Pab RbxGt | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Rat | | Concentration | ~5mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa23-37 of rat Tyr-CGRP conjugated to gamma globulin. | | Specificity | Recognizes rat Calcitonin gene-related peptide, also known as CGRP. Reacts with both the whole molecule (aa1-37) and the C-terminal fragment (23-37). Species Crossreactivity: mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Calcitonin Related Polypeptide alpha, Calcitonin Gene-related Peptide 1 Precursor |
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Download Specifications for Anti -Calcitonin Gene Related Peptide (CGRP, Calcitonin Gene-related Peptide 1, CGRP1, Calcitonin Gene-related Peptide I, CGRP I, CGRP-I, Alpha Type CGRP, CAL6, Cal1, Calc, Calcitonin 1, CALC 1, CALC 2, RATCAL6, Calcitonin-related Polypeptide alpha, CALC A, CAL |
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