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You are here:Home » Antibodies » Abs to Calcitonin » Anti -Calcitonin Gene Related Peptide (CGRP, Calcitonin Gene-related Peptide 1, CGRP1, Calcitonin Gene-related Peptide I, CGRP I, CGRP-I, Alpha Type CGRP, CAL6, Cal1, Calc, Calcitonin 1, CALC 1, CALC 2, RATCAL6, Calcitonin-related Polypeptide alpha, CALC A, CAL

Anti -Calcitonin Gene Related Peptide (CGRP, Calcitonin Gene-related Peptide 1, CGRP1,
Calcitonin Gene-related Peptide I, CGRP I, CGRP-I, Alpha Type CGRP, CAL6, Cal1, Calc,
Calcitonin 1, CALC 1, CALC 2, RATCAL6, Calcitonin-related Polypeptide alpha, CALC A, CAL

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E IH IF
CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin. Despite these important physiologic functions, therapeutic strategies using CGRP have been impeded due to the lack of a cloned CGRP receptor with which ligands could be developed.
Catalog #C0115-01D
ApplicationsSuitable for use in ELISA, Immunofluorescence and Immunohistochemistry. Not recommended for frozen or resin sections. Other applications not tested.
Recommended DilutionsELISA: 1:500-1:2500
Immunohistochemistry: Paraffin sections
Optimal dilutions to be determined by the researcher.
Recommended Secondary AntibodiesI1904-28K: IgG, H&L (HRP) Pab RbxGt
I1904-28Q: IgG, H&L, X-Adsorbed (HRP) Pab RbxGt
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceRat
Concentration~5mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa23-37 of rat Tyr-CGRP conjugated to gamma globulin.
SpecificityRecognizes rat Calcitonin gene-related peptide, also known as CGRP. Reacts with both the whole molecule (aa1-37) and the C-terminal fragment (23-37). Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCalcitonin Related Polypeptide alpha, Calcitonin Gene-related Peptide 1 Precursor


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