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You are here:Home » Antibodies » Abs to Calcitonin » Anti -Calcitonin

Anti -Calcitonin

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant IH
Calcitonin is a 32aa peptide which can be demonstrated in C cells of the normal and hyperplastic thyroid. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.
Catalog #C0115-08B
ApplicationsSuitable for use in Immunohistochemistry. Other aplications not tested.
Recommended DilutionsImmunohistochemistry (Formalin/paraffin): 1:200 for 30 minutes at RT. No special pretreatment is required for the immunohistochemical staining of formalin/paraffin tissues. Optimal dilutions to be determined by the researcher.
Recommended Positive ControlThyroid or medullary carcinoma
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG
Clone No5G25
HostRabbit
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid, 15mM sodium azide.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to aa1-32 of human calcitonin.
Cellular LocalizationCytoplasmic.
SpecificityRecognizes human Calcitonin. Species Crossreactivity: monkey, mouse, rat, canine, equine, sheep, porcine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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