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Specifications

Clone Host Grade Applications Monoclonal Rabbit Supernatant E IH

Caldesmon is a regulatory protein found in smooth muscle and other tissues which interacts with actin, myosin, tropomyosin, and calmodulin. Caldesmon antibody labels smooth muscle and tumors of smooth muscle, myofibroblastic, and myoepithelial differentiation. Caldesmon has also been used to differentiate epithelioid mesothelioma from serous papillary carcinoma of the ovary.
Catalog #	C0132-14Q
Applications	Suitable for use in Immunohistochemistry. Other applications not tested.
Recommended Dilution	Immunohistochemistry (Paraffin, frozen): 1:25-1:100
	Optimal dilutions to be determined by the researcher.
Positive Control	Smooth muscle from various sources including bowel, esophagus, uterus
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Monoclonal
Clone No	E-89
Host	Rabbit
Source	Human
Concentration	Not determined.
Form	Supplied as a liquid in PBS, pH7.4, protein base, sodium azide.
Purity	Supernatant
Immunogen	Synthetic phosphopeptide of human Caldesmon surrounding Ser789..
Specificity	Recognizes human Caldesmon. This antibody is not phospho-specific, however, and will recognize total endogenous protein. Staining pattern: Cytoplasmic.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.