Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Myosin » Anti -CtIP (RBBP-8, CtBP-interacting protein, CtIP, CTIP, Retinoblastoma-binding protein 8, Retinoblastoma-interacting protein and myosin-like, RIM)

Anti -CtIP (RBBP-8, CtBP-interacting protein, CtIP, CTIP, Retinoblastoma-binding protein
8, Retinoblastoma-interacting protein and myosin-like, RIM)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
CtIP (CtBP-interacting protein or RBBP-8) is a BRCA1- and CtBP-interacting protein that may modulate the functions ascribed to BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. Located predominantly in the nucleus, CtIP interacts with CTBP, with the C-terminal (BRCT) domains of BRCA1, and with the retinoblastoma protein. CtIP is phosphorylated upon DNA damage, probably by ATM or ATR, and is ubiquitinated by SIAH1, leading to its subsequent proteasomal degradation.
Catalog #C0807-13
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlU2OS cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenLinear peptide corresponding to CtIP (KLH). Cellular Localization: Nucleus
SpecificityRecognizes human CtIP. Species sequence homology: cow, dog, horse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links