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Calcyclin Binding Protein, aa1-185, Recombinant, Human (CACYBP, GIG5, MGC87971, PNAS-107, RP1-102G20.6, SIP, S100A6BP)
Calcyclin Binding Protein, aa1-185, Recombinant, Human (CACYBP, GIG5, MGC87971, PNAS-107,
RP1-102G20.6, SIP, S100A6BP)
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| CACYBP is primarily a nuclear protein that contains one CS domain and one SGS domain. It is believed to be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It most likely serves as a molecular bridge in Ubiquitin E3 complexes. It also participates in the Ubiquitin-mediated degradation of B-catenin. CACYBP is thought to be a potential inhibitor of cell growth and invasion in the gastric cancer cell through its effects on B-catenin protein expression and transcriptional activation of TCF/LEF. | | | Catalog # | C1031-89 | | Source | Recombinant corresponding to aa1-185 of human CACYBP 6x his tagged expressed in E.coli. | | AA Sequences | MGSSHHHHHH SSGLVPRGSH MQQKSQKKAE LLDNEKPAAV VAPITTGYTV KISNYGWDQS DKFVKIYITL TGVHQVPTEN VQVHFTERSF DLLVKNLNGK SYSMIVNNLL KPISVEGSSK KVKTDTVLIL CRKKVENTRW DYLTQVEKEC KEKEKPSYDT ETDPSEGLMN VLKKIYEDGD DDMKRTINKA WVESREKQAK GDTEF | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 23.4kD | | Source | E.coli | | Purity | ~85% (SDS-PAGE) | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol, 1mM DTT, 0.1M sodium chloride. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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