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You are here:Home » Antibodies » Abs to Calmodulin » Anti -Calmodulin (CALM 1, CALM 2, CALM 3, CALM, CALM1, CALM2, CALM3, CALML2, CAM 1, CAM 2, CAM 3, CAM I, CAM1, CAM2, CAM3, CAMB, CAMC, CAMI, CAMIII, CaM, Calmodulin 1, Calmodulin1, DD132, PHKD, Phosphorylase kinase delta, Phosphorylase kinase delta subunit)

Anti -Calmodulin (CALM 1, CALM 2, CALM 3, CALM, CALM1, CALM2, CALM3, CALML2, CAM 1, CAM 2,
CAM 3, CAM I, CAM1, CAM2, CAM3, CAMB, CAMC, CAMI, CAMIII, CaM, Calmodulin 1, Calmodulin1,
DD132, PHKD, Phosphorylase kinase delta, Phosphorylase kinase delta subunit)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E B IC
Calmodulin is a small, highly conserved calcium binding protein found in all eukaryotic cells. With the capacity to bind up to four calcium ions, this 17kD protein acts as an important intracellular receptor for regulatory calcium signals. As it binds calcium, calmodulin undergoes conformational changes which can increase its affinity for target proteins. It acts both directly, through interaction with key target enzymes, and indirectly, via specific kinases. Studies have found that calmodulin participates in the regulation of several biological processes including energy and biosynthetic metabolism, cell motility, exocytosis, cytoskeletal assembly, and intracellular modulation of both cAMP and calcium concentrations.
Catalog #C1035-01C
ApplicationsSuitable for use in ELISA, Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: Detects a 17kD protein representing calmodulin from Dictyostelium cell lysate.
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No8J483
HostMouse
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.
PurityAscites
ImmunogenCalmodulin purified from Dictyostelium discoideum.
SpecificityThis antibody detects calmodulin. It does not detect parvalbumin, tropinin, S-100, or myosin light chain kinase (MLCK). Species Crossreactivity: Crossreacts with bovine, chicken, E. coli, rat, Chlamydomonas reinhardtii and Dictyostelium discoideum.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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