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You are here:Home » Antibodies » Abs to Calpain » Anti -CAPN10, NT (Calpain-10, Calcium-activated Neutral Proteinase 10, CANP 10, KIAA1845)

Anti -CAPN10, NT (Calpain-10, Calcium-activated Neutral Proteinase 10, CANP 10, KIAA1845)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B
CAPN10 is ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. This protein is heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. The protein is similar in organization to calpains 5 and 6.
Catalog #C1035-30E
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Numbern/a
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.25mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenSynthetic peptide selected from the N-terminal region of human CAPN10 (KLH).
SpecificityRecognizes human CAPN10.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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