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You are here:Home » Antibodies » Antibodies-Nitric Oxide » Anti -CAPON (Carboxyl-terminal PDZ Ligand of Neuronal Nitric Oxide Synthase Protein, C-terminal PDZ Ligand of Neuronal Nitric Oxide Synthase Protein, Nitric Oxide Synthase 1 Adaptor Protein, NOS1AP, KIAA0464)

Anti -CAPON (Carboxyl-terminal PDZ Ligand of Neuronal Nitric Oxide Synthase Protein,
C-terminal PDZ Ligand of Neuronal Nitric Oxide Synthase Protein, Nitric Oxide Synthase 1
Adaptor Protein, NOS1AP, KIAA0464)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E IH
Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4.
Catalog #C1035-39A
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA (Peptide): 1:1000
Immunohistochemistry (Paraffin): 4-6ug/ml Requires steam antigen retrieval with Tris/EDTA buffer pH9.5
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to PSKTKYNLVDDGH-C, from the N-terminal of human CAPON,(NP_055512.1, NP_001158229.1). Species sequence homology: bovine, mouse and rat.
SpecificityRecognizes human CAPON.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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