You are here:Home
»
Antibodies
»
Abs to Calretinin
»
Anti -Calretinin (CR, Calbindin 2, Calb2)
Anti -Calretinin (CR, Calbindin 2, Calb2)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
IH |
|
| Calretinin is an intracellular calcium-binding protein belonging to the troponin C superfamily. The sequence of the calretinin cDNA revealed an open reading frame of 271 codons coding for a protein of 31 520 Da, and sharing 58% identical residues with Human calbindin D28k. It contains five presumably active and one presumably inactive calcium-binding domain. The protein is highly conserved in evolution and is expressed in the brain mianly in the auditory neurons. There are two additional forms of alternatively spliced calbindin 2 mRNAs encoding C-terminally truncated proteins. Exon 7 can splice to exon 9, resulting in a frame shift and a translational stop at the second codon of exon 9, and encoding calretinin-20k. Exon 7 can also splice to exon 10, resulting in a frame shift and a translational stop at codon 15 of exon 10, and encoding calretinin-22k. The truncated proteins are able to bind calcium. It is mapped to 16q22.2 region of Human chromosome. | | | Catalog # | C1036-01V | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin): 1:50-1:100 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Mesothelioma | | Cellular Localization | | | Cytoplasmic | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Mouse | | Concentration | Not determined | | Form | Supplied as a liquid in 0.05% sodium azide. | | Purity | Serum | | Immunogen | Recombinant full length mouse Calretinin protein. | | Specificity | Recognizes human Calretinin. Species Crossreactivity: mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
