| Candida albicans is a diploid fungus (a form of yeast) and a causal agent of opportunistic oral and genital infections in humans. Systemic fungal infections (fungemias) have emerged as important causes of morbidity and mortality in immunocompromised patients (e.g., AIDS, cancer chemotherapy, organ or bone marrow transplantation). In addition, hospital-related infections in patients not previously considered at risk (e.g., patients in an intensive care unit) have become a cause of major health concern. C. albicans is commensal and is among the gut flora, the many organisms which live in the human mouth and gastrointestinal tract. Under normal circumstances, C. albicans lives in 80% of the human population with no harmful effects, although overgrowth results in candidiasis. Candidiasis is often observed in immunocompromised individuals such as HIV-positive patients. Candidiasis also may occur in the blood and in the genital tract. Candidiasis, also known as "thrush", is a common condition which is usually easily cured in people who are not immunocompromised. To infect host tissue, the usual unicellular yeast-like form of C. albicans reacts to environmental cues and switches into an invasive, multicellular filamentous forms |
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| Catalog # | C1075-01A |
| Applications | Suitable for use in ELISA, Immunofluorescence, Immunohistochemistry, Double Diffusion, Conjugation and Counter Immunoelectrophoresis. Other applications have not been tested. |
| Recommended Dilutions | Gel-precipitin reactions: Neat |
| Optimal dilutions to be determined by the researcher. |
| Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| CAS Number | n/a |
| Clone Type | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Concentration | ~4-5mg/ml |
| Form | Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. Glycerol Free. No stabilizing proteins added. |
| Purity | Purified by Protein A affinity chromatography. |
| Immunogen | Candida albicans, type A (ATCC #32354), C. albicans (Robin) Berkhout |
| Specificity | Recognizes numerous proteins in a soluble C. albicans extract (IEP). Has not been adsorbed. Does crossreact with other yeasts. Negative vs. human serum, urine and spinal fluid. |
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| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
