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Canertinib, Dihydrochloride (N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide Dihydrochloride, CI-1033, PD183805)
Canertinib, Dihydrochloride
(N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-prop
enamide Dihydrochloride, CI-1033, PD183805)
Pricing
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| Canertinib (CI-1033, PD 183805) is a pan-erbB tyrosine kinase inhibitor. It selectively inhibits erbB1 (epidermal growth factor receptor), erbB2, erbB3, and erbB4 without blocking tyrosine kinase activity of many other receptors such as platelet-derived growth factor receptor, fibroblast growth factor receptor, and insulin receptor. | | | Catalog # | C1075-25 | | Solubility | Soluble in DMSO at 100mg/ml; soluble in ethanol at 1mg/ml with warming; soluble in water at 10mg/ml with warming; buffers, serum, or other additives may increase or decrease the aqueous solubility. Compound is somewhat unstable in HPLC sample solution at room temperature. | | Storage and Stability | May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. | | CAS Number | 289499-45-2 | | Molecular Formula | C24H25ClFN5O3•2HCl | | Molecular Weight | 558.86 | | Purity | ~99% | | Form | Supplied as an off-white to pale green powder. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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