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Capecitabine (5’-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine, Ro-9-1978, Xeloda)
Capecitabine (5’-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine, Ro-9-1978, Xeloda)
Pricing
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| Capecitabine is a pre-prodrug of 5-fluorouracil (5-FU). After oral uptake, capecitabine is first metabolized to 5'-deoxy-5-fluorocytidine (5'-DFCR), which happens mainly in the liver by carboxyl-esterase. The metabolite is converted to 5'-deoxy-5-fluoro-uridine (5'-DFUR) by cytidine deaminase in liver and tumor tissue. Then 5'-DFUR is converted to 5-FU intracellularly by thymidine phosphorylase, which is often expressed in tumor tissue. | | | Catalog # | C1077-05B | | Solubility | Soluble in DMSO at 100mg/ml; soluble in ethanol at 12.5mg/ml with slight warming; soluble in water at 2mg/ml with slight warming; buffers, serum, or other additives may increase or decrease the aqueous solubility. | | Storage and Stability | May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. | | CAS Number | 154361-50-9 | | Molecular Formula | C15H22FN3O6 | | Molecular Weight | 359.35 | | Purity | ~99% | | Form | Supplied as a white to off-white powder. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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