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Anti -Capsaicin Receptor (VR1, Transient receptor potential cation channel subfamily V member 1, TrpV1, osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, Vanilloid receptor type 1-like)
Anti -Capsaicin Receptor (VR1, Transient receptor potential cation channel subfamily V
member 1, TrpV1, osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, Vanilloid
receptor type 1-like)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
IH |
|
| VR1 (vanilloid receptor 1) is an ion channel activated by capsaicin, the pungent ingredient in hot peppers, and by noxious thermal heat. It is expressed by and isolated from nociceptive sensory neurons. Sequence analysis suggests that VR1 has transmembrane domains and intracellular N- and C-termini. It shares structural similarities with the family of putative store-operated calcium channels. It is thought to function as a transducer of noxious thermal stimuli and have involvement in inflammatory pain. | | | Catalog # | C1078 | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry: 1:2000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute by adding sterile 40-50% glycerol, PBS. Aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Rat | | Concentration | Not determined | | Form | Supplied as a lyophilized powder. No preservative added. Reconstitute in 50ul of ddH2O or a 40-50% glycerol. | | Purity | Serum | | Immunogen | A 21 amino acid peptide corresponding to the C-terminus of the Capsaicin Receptor protein. | | Specificity | Recognizes rat Capsaicin Receptor (Vanilloid Receptor 1, VR1). Reacts well with tissue from the rat dorsal root ganglia. Species crossreactivity: human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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