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You are here:Home » Antibodies » Abs to Ion Channel » Anti -Capsaicin Receptor (VR1, Transient receptor potential cation channel subfamily V member 1, TrpV1, osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, Vanilloid receptor type 1-like)

Anti -Capsaicin Receptor (VR1, Transient receptor potential cation channel subfamily V
member 1, TrpV1, osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, Vanilloid
receptor type 1-like)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E B
VR1 (vanilloid receptor 1) is an ion channel activated by capsaicin, the pungent ingredient in hot peppers, and by noxious thermal heat. It is expressed by and isolated from nociceptive sensory neurons. Sequence analysis suggests that VR1 has transmembrane domains and intracellular N- and C-termini. It shares structural similarities with the family of putative store-operated calcium channels. It is thought to function as a transducer of noxious thermal stimuli and have involvement in inflammatory pain.
Catalog #C1078-01
ApplicationsSuitable for use in Western Blot and ELISA. Other applications not tested.
Recommended DilutionsWestern Blot: 1:1000--5000 using ECL. Recombinant VR1 is ~90kD
ELISA: 1:10,000--50,000. Control peptide can be used to coat ELISA plates at 1ug/ml.
Optimal dilutions to be determined by the researcher.
Control PeptideC1078-01E: Capsaicin Receptor, Rat, Control Peptide
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceRat
ConcentrationNot Determined
FormSupplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.
PuritySerum
ImmunogenSynthetic peptide corresponding to 15aa to the C-terminus, cytoplasmic domain of rat Capsaicin Receptor. Species Sequence Homology: guinea pig, mouse and chicken; 93%, human; 63%
SpecificityRecognizes rat Capsaicin Receptor. No significant sequence homology with VRL-1 or TRP or other proteins.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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