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You are here:Home » Antibodies » Abs to Ion Channel » Anti -Capsaicin Receptor (VR1, Transient receptor potential cation channel subfamily V member 1, TrpV1, osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, Vanilloid receptor type 1-like)

Anti -Capsaicin Receptor (VR1, Transient receptor potential cation channel subfamily V
member 1, TrpV1, osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, Vanilloid
receptor type 1-like)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
VR1 (vanilloid receptor 1) is an ion channel activated by capsaicin, the pungent ingredient in hot peppers, and by noxious thermal heat. It is expressed by and isolated from nociceptive sensory neurons. Sequence analysis suggests that VR1 has transmembrane domains and intracellular N- and C-termini. It shares structural similarities with the family of putative store-operated calcium channels. It is thought to function as a transducer of noxious thermal stimuli and have involvement in inflammatory pain.
Catalog #C1078-05
Application(s)Immunohistochemistry: 1-2ug/ml
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add glycerol (40-50%) and store at -20°C. Do not freeze. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceRat
Concentration~1mg/ml
FormSupplied as a lyophilized powder. No preservative added.
PurityAffinity Purified
ImmunogenA 21 amino acid peptide corresponding to the C-terminus of the rat Capsaicin Receptor protein
SpecificityRecognizes Capsaicin Receptor (Vanilloid Receptor 1, VR1). Reacts well with tissue from the rat dorsal root ganglia. Species Reactivity: Human and rat.
Important NoteThis product is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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