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You are here:Home » Antibodies » Abs to Enzymes, Synthetase » Anti -Carbamoyl Phosphate Synthetase 1 (Carbamoyl-phosphate Synthetase 1 Mitochondrial, Carbamoylphosphate Synthetase 1, Carbamoyl Phosphate Synthetase I, Carbamoylphosphate Synthetase I, CPS 1, CPS1, CPSase 1, CPSase I, Carbamoyl Phosphate Synthase [ammonia] M

Anti -Carbamoyl Phosphate Synthetase 1 (Carbamoyl-phosphate Synthetase 1 Mitochondrial,
Carbamoylphosphate Synthetase 1, Carbamoyl Phosphate Synthetase I, Carbamoylphosphate
Synthetase I, CPS 1, CPS1, CPSase 1, CPSase I, Carbamoyl Phosphate Synthase [ammonia] M

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH
The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.
Catalog #C1080-98-FITC
ApplicationsSuitable for use in Western Blot, FLISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 1.5ug/ml
FLISA: 1ug/ml-3ng/ml
Western Blot: 1:500-1:1000
Optimal dilutions to be determined by the researcher.
HybridomaSp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10B2589
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to FITC.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant protein corresponding to a portion of amino acids within aa1400-1501 of human CPS1.
SpecificityRecognizes human CPS1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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