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You are here:Home » Antibodies » Abs to Apoptosis, Caspase » Anti -CARD4 (Nucleotide-binding Oligomerization Domain-containing Protein 1, Caspase Recruitment Domain-containing Protein 4, NOD1)

Anti -CARD4 (Nucleotide-binding Oligomerization Domain-containing Protein 1, Caspase
Recruitment Domain-containing Protein 4, NOD1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Nod1 is implicated in the intracellular detection of pathogen associated molecule, such as, microbial peptidoglycans and signals the activation of NF-kB. Nod1 has an NH2-terminal CARD-linked to a nucleotide-binding domain and a COOH-terminal segment with multiple leucine-rich repeats, which are involved in binding to multiple caspases with long prodomains, but specifically activated caspase-9 and promoted caspase-9-induced apoptosis. Nod1 is a leucine-rich repeat-containing Apaf-1-like molecule that can regulate both apoptosis and NF-kB activation pathways.
Catalog #C1340-01E
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:2500
Optimal dilutions to be determined by the researcher.
Positive ControlRecombinant fusion protein
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid, 0.025% sodium azide, 50% glycerol.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa930-949 of human Nod1.
SpecificityRecognizes human CARD4. Species sequence homology: mouse and monkey.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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