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You are here:Home » Growth Factors, Cytokines » Growth Factors-Cardiotrophin » Cardiotrophin 1, Human, Recombinant (CT1)

Cardiotrophin 1, Human, Recombinant (CT1)

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Specifications

Human Cardiotrophin-1 is a member of the leukemia inhibitory/ciliary neurotrophic factor/Oncostatin M/interleukin-6/interleukin-11 family of cytokines. Cardiotrophin-1 affects cells through interaction with the gp130 receptor subunit. Human Cardiotrophin-1 is a 21.5kD protein containing 201 amino acid residues.
Catalog #C1385-06
Biological Activity The ED50 as determined by the dose-dependent proliferation of TF-1 cells was < 1.0ng/ml, corresponding to a speci c activity of > 1x10e6units/mg
AA Sequence MSRREGSLED PQTDSSVSLL PHLEAKIRQT HSLAHLLTKY AEQLLQEYVQ LQGDPFGLPS FSPPRLPVAG LSAPAPSHAG LPVHERLRLD AAALAALPPL LDAVCRRQAE LNPRAPRLLR RLEDAARQAR ALGAAVEALL AALGAANRGP RAEPPAATAS AASATGVFPA KVLGLRVCGL YREWLSRTEG DLGQLLPGGS A
Storage and Stability Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 20mM Tris, pH 8.0 and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Country of Origin: USA
Molecular Weight21.5kDa
SourceRecombinant, Human (E. coli)
Purity98% by SDS-PAGE and HPLC analyses. Endotoxin: 0.1ng/ug (1EU/ug)
FormSupplied as a lyophilized powder from PBS. Reconstitute in 20mM Tris, pH 8.0, to a concentration of 1mg/ml. This solution can then be diluted into other aqueous solutions.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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