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You are here:Home » Growth Factors, Cytokines » Growth Factors-Cardiotrophin » Cardiotrophin 1, Recombinant, Human (CT1)

Cardiotrophin 1, Recombinant, Human (CT1)

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Specifications

Catalog #C1385-06A
SourceRecombinant corresponding to 201aa from human Cardiotrophin 1 expressed in E. coli.
Molecular Weight~21.5kD
ActivityED50 <1.0 ng/ml (>1 x 106units/mg). The biological activity was determined by measuring the dose-dependent proliferation of TF-1 cells. Cardiotrophin-1 is a member of the IL-6 family of cytokines which includes IL-6, Leukemia Inhibitory Factor, Ciliary Neurotrophic Factor, Oncostatin M and Interleukin 11. The receptor for Cardiotrophin-1 is gp130 (CD130). Cardiotrophin-1 was originally identified by its ability to stimulate cardiac hypertrophy. As with all members of the IL-6 family of cytokines, Cardiotrophin-1 induces hepatic expression of acute phase proteins.
Endotoxin <0.1 ng/ug
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~21.5kD
SourceE. coli
Purity~98% (SDS PAGE, HPLC)
ConcentrationNot determined
FormSupplied as a lyophilized powder in PBS. Reconstitute with sterile dH2O PBS to 0.1-1mg/ml.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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