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Abs to Catenin
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Anti -Catenin, alpha, CT (Catenin alpha-1, Alpha E-catenin, Cadherin-associated Protein, Renal Carcinoma Antigen NY-REN-13, CTNNA1)
Anti -Catenin, alpha, CT (Catenin alpha-1, Alpha E-catenin, Cadherin-associated Protein,
Renal Carcinoma Antigen NY-REN-13, CTNNA1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| The catenins (alpha, beta and gamma) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin. alpha-catenin can also bind P-cadherin and N-cadherin. alpha-catenin exhibits both actin binding and bundling activities. Cadherin/catenin complexes are linked to the cytoskeleton via a direct association between alpha-actinin and alpha-catenin. Increased tyrosine phosphorylation can disrupt catenin-cadherin complexes, influencing cellular adhesion. | | | Catalog # | C2069-44B | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 2.5-5ug/ml | | Immunohistochemistry: 1:300 for 10min at RT | | Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10min followed by cooling at RT for 20min | | Optimal dilutions to be determined by the researcher. | | Positive Control | A431 and MCF-7 cells | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to human Catenin alpha at C-terminal. | | Specificity | Recognizes human Catenin alpha. Species Crossreactivity: mouse, xenopus. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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