Anti -Catenin, beta (Beta Catenin, Cadherin-associated Protein, Catenin beta 1, CATNB,
CTNNB, CTNNB1, FLJ25606, FLJ37923, OK/SW-cl.35, PRO2286)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IP IF |
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| Beta-catenin belongs together with alpha- and gamma-catenin to the catenin family. Catenins mediates cell-cell adhesion by interaction with cadherins. Beta-catenin is highly homologous to gamma-catenin (plakoglobin) although its function differs from that of plakoglobin. Whereas plakoglobin has been found to suppress tumorigenicity, beta-catenin potentiates hyperproliferation and tumor formation. In the nucleus beta-catenin it complexes with transcription factors and thus regulates the expression of specific genes. By its dual role, i.e. a structural role in cell-cell junctions and a regulatory role in the nucleus, beta-catenin can transduce changes in cell adhesion and junction formation to control transmembrane signalling and gene expression | | | Catalog # | C2069-50R | | Applications | Suitable for use in Immunofluorescence, Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Immunoflourescence: 1:10 Fix cells with paraformaldehyde. | | Western Blot: 1:10 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 9F2 | | Host | Mouse | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Human beta-Catenin. | | Specificity | Recognizes human beta-Catenin. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Catenin (Cadherin-associated Protein), beta 1, 88kDa, DKFZp686D02253 |
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Download Specifications for Anti -Catenin, beta (Beta Catenin, Cadherin-associated Protein, Catenin beta 1, CATNB, CTNNB, CTNNB1, FLJ25606, FLJ37923, OK/SW-cl.35, PRO2286) |
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