Anti -Catenin, delta 1 (CTNND1, Cadherin-Associated Protein delta 1, Cadherin-associated
Src Substrate, CAS, p120 Catenin, p120(ctn), p120(cas), KIAA0384)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP |
|
| CTNND1 is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Further, it binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway and promotes GLIS2 C-terminal cleavage. | | | Catalog # | C2069-54G | | Applications | Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Immunoprecipitation: 2-5ug/mg | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in Tris-citrate/phosphate buffer, pH 7-8, 0.09% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to a region between aa625-675 of human Catenin, delta 1. | | Specificity | Recognizes human Catenin, delta 1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | CTNND, CTNND-1, CTNND1, catenin (cadherin-associated protein), delta 1, CAS, P120CAS, P120CTN, cadherin-associated protein |
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