Anti -Catenin, delta 1 (Cadherin-associated Src Substrate, CAS, Catenin Delta-1, CTNND,
KIAA0384, p120, p120(cas), p120(ctn), p120cas, P120CAS, p120 Catenin, p120ctn, P120CTN)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Supernatant |
B IP IH IC FC |
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| Catenins are proteins associated with complexes that contain cadherin cell adhesion molecules. Delta-1-catenin is a member of the p120 Catenin subfamily and is a structural protein involved in neuronal development. It interacts with Actin, Cortactin and Src Kinases to promote neurite elongation or branching, depending upon its phosphorylation state. Like beta-catenin and gamma-catenin, delta-catenins appear to interact with presenilins. These catenin-presenilin interactions can impact cadherin function and regulation of cell-to-cell adhesion. While beta-catenin acts as a transcription regulatory protein in the Wnt/TCF pathway, delta-catenin has been implicated as a regulator of the NF-kB transcription factor. | | | Catalog # | C2069-54Q | | Applications | Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 1:50 | | Western Blot: 1:250-1:1000 | | Immunohistochemistry: 1:100-1:250 | | Immunocytochemistry: 1:250 | | Immunoprecipitation: 1:80 | | Optimal dilutions to be determined by the researcher. | | Positive Control | HeLa whole cell lysate | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 9H209 | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA. | | Purity | Supernatant. | | Immunogen | Synthetic peptide directed against the N-terminus of human Catenin delta-1. Cellular Localization | | Specificity | Recognizes human Catenin delta-1. Not expected to react with mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Catenin, delta 1 (Cadherin-associated Src Substrate, CAS, Catenin Delta-1, CTNND, KIAA0384, p120, p120(cas), p120(ctn), p120cas, P120CAS, p120 Catenin, p120ctn, P120CTN) |
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