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You are here:Home » Antibodies » Abs to Connexin, Junction Proteins » Anti -Catenin, gamma (Catenin gamma, CTNNG, Desmoplakin 3, Desmoplakin-3, DP3, Desmoplakin III, Desmoplakin-III, DPIII, Gamma Catenin, Junction Plakoglobin, JUP)

Anti -Catenin, gamma (Catenin gamma, CTNNG, Desmoplakin 3, Desmoplakin-3, DP3, Desmoplakin
III, Desmoplakin-III, DPIII, Gamma Catenin, Junction Plakoglobin, JUP)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH IC IF
Junction Plakoglobin (JUP), also knows as catenin gamma, is a major cytoplasmic protein that occurs in a soluble and a membrane-associated form and is the only known constituent common to the submembranous plaques of both kinds of adhering junctions, the desmosomes and the intermediate junctions. It is a component of the cadherin-catenin complex, which is predominantly localized where actin filaments anchor in adherens junctions of epithelial cells. The human plakoglobin gene localizes on chromosome 17q21. Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin.
Catalog #C2069-55D
ApplicationSuitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry, and Immunofluorescence. Other applications not tested.
Recommended DilutionWestern Blot: 2ug/ml
Immunohistochemistry (frozen): 4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH20. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10K129
HostMouse
SourceChicken
ConcentrationAs reported
FormSupplied as a lyophilized powder from 1.2% sodium acetate, 2mg BSA, 0.01mg sodium azide. Reconstitute with 1.2% sodium acetate, PBS.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant chicken plakoglobin.
SpecificityRecognizes chicken Catenin gamma. Species Crossreactivity: human, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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